Meglumine
Industrial Applications
Meglumine is widely utilized in the pharmaceutical and medical imaging industries due to its ability to enhance solubility and stability of active ingredients. It is a key component in the formulation of iodinated contrast media used in X-ray and Computed Tomography (CT) imaging, where it helps improve the safety and performance of diagnostic agents. Beyond imaging, Meglumine serves as a solubilizing and stabilizing excipient in drug manufacturing and can be incorporated as a buffering agent to adjust formulation pH. Its compatibility with a broad range of pharmaceutical compounds makes it valuable in the production of injectable solutions, oral medications, and topical formulations.
Physical Properties
Meglumine is a white, hygroscopic, crystalline organic compound that readily absorbs moisture from the environment. It exhibits high solubility in water due to its polyhydroxylated amine structure, which enables strong hydrogen bonding. Meglumine is non-volatile and thermally stable under typical processing conditions, making it suitable for use in sterile and heat-treated pharmaceutical formulations. Its mild basicity contributes to its function as a pH-adjusting agent in various drug products.
Grade
- DMF
Other Names
- N-Methylglucamine
- Glucamine
Abbreviations
- MG
Form
- Solid
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